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1:31
YouTube
Peter Attia MD
Fluffy LDL particles and cardiovascular risk | Jim Otvos, Ph.D.
This clip is from episode # 402 of The Drive which was released on 8/3/26. In the full episode, we cover: - Why LDL particle number can reveal cardiovascular risk that LDL cholesterol alone misses, and how the two can disagree -Why the popular idea that large, "fluffy" LDL particles are benign does not hold up, and the genetic condition that ...
56.2K views
4 weeks ago
Watch full video
LDL Cholesterol Explained
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heart blockage , Cholesterol TREATMENT, Triglycerides Diet, Cholesterol Symptoms, High Cholesterol
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LDL IS UNDEFEATED! No matter how we have lower cholesterol and whether it's through diet
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viyalum
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A cholesterol breakthrough medication just became available. Lipfendra (enlicitide) is a groundbreaking prescription medication from Merck that was approved by the FDA in July 2026 as the world's first once-daily oral pill to lower bad cholesterol (LDL-C). It works by blocking the PCSK9 protein, which helps the liver aggressively clear cholesterol from the bloodstream. This daily tablet offers a highly effective, needle-free alternative for patients who previously had to rely on painful bi-weekl
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Not every cholesterol case is straightforward. A 24-year-old with an LDL of 105 mg/dL, but an ApoB of 135 mg/dL and Lp(a) of 240—despite an excellent diet. This is where medicine gets nuanced. LDL alone doesn’t tell the whole story. Genetics, ApoB, Lp(a), family history, lifetime cardiovascular risk, and shared decision-making all come into play. Sometimes the answer isn’t obvious, and that’s exactly why personalized care matters.
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