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jove.com
Video: Preparation of Alkynes: Alkylation Reaction
10.9K Views. Introduction Alkylation of terminal alkynes with primary alkyl halides in the presence of a strong base like sodium amide is one of the common methods for the synthesis of longer carbon-chain alkynes. For example, treatment of 1-propyne with sodium amide followed by reaction with ethyl bromide yields 2-pentyne.
Mar 3, 2023
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