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Introducing #RANKL-targeting drugs and #MEK1/2 inhibitors: #dengyuemed

Introducing #RANKL-targeting drugs and #MEK1/2 inhibitors: #dengyuemed

🎯 RANKL Inhibitors: Narlumosbar & Denosumab 📌 Narlumosbart A fully human IgG4 monoclonal antibody that binds RANKL to inhibit osteoclast activity and prevent bone resorption Approved in China (Sept 2023) for unresectable giant cell tumor of bone; being studied for bone metastases and osteoporosis 📌 Denosumab (#Prolia/#Xgeva) A human ...

107 views11 months ago

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Denosumab injInhibits RANKL and used for Osteoporosis

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Before anyone asks yes osteoperotic drugs during puberty will cause osteoblast activation and it will make you taller just because there isn’t nearly enough studies on pre epiphysial plate closure osteoblast activation using these drugs doesent mean it doesent work and denosumab and rankl is one of the most important pathways for optimizing osteoblast during growth phases #osteoperosis #osteoblast #pharmecology #bones

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