Semaglutide - ALZFORUM
Semaglutide is a synthetic, long-acting analog of glucagon-like peptide-1, used to treat diabetes. Ozempic TM is a once-per-week injection formulation, while Rybelsus TM is is a daily pill. Rybelsus TM was approved by the U.S. FDA in September 2019 as the first GLP-1 analog that does not need to be injected.
Novel LC-MS/MS analysis of the GLP-1 analog semaglutide with its ...
Novel LC-MS/MS analysis of the GLP-1 analog semaglutide with its application to pharmacokinetics and brain distribution studies in rats. J Chromatogr B Analyt Technol Biomed Life Sci. 2023 Apr 15;1221:123688. Epub 2023 Mar 22 PubMed. Recommends. Please login to recommend the paper. Comments. No Available Comments. Make a Comment
Semaglutide as a possible therapy for healthy aging: Targeting the ...
Jan 8, 2025 · Semaglutide as a possible therapy for healthy aging: Targeting the hallmarks of aging. Ageing Res Rev. 2024 Dec;102:102582. Epub 2024 Nov 14 PubMed. Recommends. Please login to recommend the paper. Comments. No Available Comments. Make a Comment. To make a comment you must login or register.
Could GLP-1 Receptor Agonists Like Semaglutide Treat Addiction ...
Could GLP-1 Receptor Agonists Like Semaglutide Treat Addiction, Alzheimer Disease, and Other Conditions?. JAMA. 2024 May 14;331(18):1519-1521. PubMed. Recommends. Please login to recommend the paper. Comments. No Available Comments. Make a Comment. To make a comment you must login or register.
Semaglutide Attenuates Anxious and Depressive-Like Behaviors …
Semaglutide Attenuates Anxious and Depressive-Like Behaviors and Reverses the Cognitive Impairment in a Type 2 Diabetes Mellitus Mouse Model Via the Microbiota-Gut-Brain Axis. J Neuroimmune Pharmacol . 2024 Jul 23;19(1):36.
The Discovery and Development of Liraglutide and Semaglutide
The Discovery and Development of Liraglutide and Semaglutide. Front Endocrinol (Lausanne). 2019;10:155. Epub 2019 Apr 12 PubMed. Recommends. Please login to recommend the paper. Comments. No Available Comments. Make a Comment. To make a …
Analysis of semaglutide's effect on Alzheimer's disease risk.
Hsu CK, Lai CC.Analysis of semaglutide's effect on Alzheimer's disease risk. Alzheimers Dement. 2024 Dec 31; Epub 2024 Dec 31 PubMed.
Liraglutide - ALZFORUM
Sep 23, 2024 · Diabetes, high blood sugar, and insulin resistance are all associated with dementia. In Alzheimer’s disease, there is evidence for insulin resistance in the brain. Thus, there has been much interest in testing liraglutide and other GLP-1 analogs, such as exendin-4, semaglutide, and lixisenatide, as potential therapeutics for AD.
Dapagliflozin - ALZFORUM
Mar 9, 2020 · Type 2 diabetes is a risk factor for developing dementia, and people with Alzheimer’s disease display signs of insulin resistance in the brain. These findings have spurred testing of multiple classes of diabetes drug for the treatment or prevention of AD (for example, see nasal insulin, pioglitazone, metformin, liraglutide and semaglutide).
Associations of semaglutide with first-time diagnosis of …
Wang W, Wang Q, Qi X, Gurney M, Perry G, Volkow ND, Davis PB, Kaelber DC, Xu R.Associations of semaglutide with first-time diagnosis of Alzheimer's disease in patients with type 2 diabetes: Target trial emulation using nationwide real-world data in the US.