Objective Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency is an inherited adrenal steroid synthesis ...

Background and objective Cardiorespiratory polygraphy (CRP) is the predominant technology used to diagnose obstructive sleep apnoea (OSA) in tertiary centres in the UK. Nocturnal pulse oximetry (NPO) ...

Our aim was to develop guidance for general paediatricians and primary care physicians in diagnosing and managing cow’s milk protein allergy in infants. The guidelines were developed by discussion ...

In this review, we provide a state of the art of liver transplantation in children, as the procedure is now carried out for more than 30 years and most of our paediatric colleagues are managing these ...

Aims: To investigate whether weight category (underweight, average weight, overweight, and obese) at age 7.5 predicts bullying involvement at 8.5 years. Models were tested separately for boys and ...

Background Most guidelines recommend the use of capillary refill time (CRT) as part of the routine assessment of unwell children, but there is little consensus on the optimum method of measurement and ...

Background We sought to measure the diagnostic accuracy of D-dimer in children with suspected pulmonary embolism (PE). Methods We queried our electronic medical record for quantitative D-dimer values ...

The heart and lungs work closely to meet the tissues’ oxygen demands. If the balance between oxygen demand and supply becomes disturbed in critical illness, tissue hypoxia and cell death can rapidly ...

AIM To determine the incidence of hypocalcaemia in critically ill children with meningococcal disease. METHODS In a prospective cohort study, 70 of 80 patients admitted consecutively with a clinical ...

Introduction With approximately 50% of the drugs being prescribed off-label, the pediatric population is in need for an innovative approach to establish harmonized, best evidence-based dosing ...

Objectives Babies born to mothers living in more deprived areas are at a higher risk of dying during the neonatal period.1 Pre-term and unwell term babies are cared for in neonatal intensive units ...

Introduction Deliberate self harm (DSH) is a major public health issue affecting 1 in 15 young people in the UK. Madge et al (2008) reported that over 70% of 15–16 year-olds admitted to self-harming ...