The concentration of hCG doubles roughly every 31 hours until concentrations in maternal serum stabilize between 8 and 12 weeks into pregnancy. hCG levels then decline slowly until term.

Disclosures Expert Rev Clin Immunol. 2012;8 (8):747-753. Expert Commentary hCG is of critical importance in the establishment of the early embryo in the harsh environment of the maternal endometrium.

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