In the field of cancer research, understanding the cellular machinery involved in malignancy and drug resistance is crucial for developing effective ...

Researchers at Duke University used CRISPR technologies to discover previously unannotated stretches of DNA in the "dark ...

The emergence of drug resistance remains one of the greatest challenges in effective cancer therapy. Despite advances in ...

Chronic kidney disease (CKD) affects more than 10% of the global population and is expected to become the fifth leading cause of death worldwide within the next two decades. Perhaps surprisingly, ...

Whereas antiphospholipid syndrome (APS) is best known for increasing the risk of macrovascular thrombosis, APS vasculopathy is characterized by the abnormal proliferation of endothelial and smooth ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Cells that activate an epithelial-mesenchymal ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Toll-like receptor 4 (TLR4) signaling at the ...

Cutaneous squamous-cell carcinoma (SCC) is primarily caused by oncogenesis mediated by ultraviolet radiation, and β-human papillomavirus (β-HPV) is believed to be a mere facilitator that is ...

National Key Laboratory for Tea Plant Germplasm Innovation and Resource Utilization, School of Tea Science, Anhui Agricultural University, Hefei, Anhui 230036, P.R. China National Key Laboratory for ...

Stanford researchers discovered that dialing down an overactive enzyme, LRRK2, can regrow lost cellular “antennae” in key brain cells, restoring vital dopamine communication and neuroprotective ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Proliferating cell nuclear antigen (PCNA) is a central regulator of numerous cellular ...