The deubiquitinase USP17LA negatively regulates T-cell activation and attenuates anti-tumor immunity
USP17LA loss enhances T-cell function and anti-tumor activity in murine tumor models. Usp17la-deficient T cells exhibit ...
Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through ...
The cell nucleus goes a long way during an immune response, both literally and figuratively. New research published in Science Immunology shows that in some white blood cells, this genetic storage ...
11hon MSN
Scientists reveal functional RNA splitting mechanism behind origin of type V CRISPR systems
CRISPR-Cas systems are adaptive immune systems found in prokaryotes that defend against invading nucleic acids through CRISPR ...
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How maternal microbes shape babies’ gut health and disease risk
Early microbial exposures from maternal microbes, milk components, and the environment shape infant gut development and ...
Cilia and flagella are microtubule-based organelles that extend from the surface of eukaryotic cells and play pivotal roles ...
A healthy brain maintains a harmony of neurons that excite or inhibit other neurons, but the lines between different types of ...
ADHD affects millions across the lifespan, disrupting school, work and relationships. Once seen as a childhood disorder, it’s ...
It is now well accepted that cells of the nervous and immune systems communicate through bidirectional signaling mediated by the release of cytokines, ...
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