Researchers filmed the enzyme APE1 hunting DNA damage one molecule at a time. Its shapeless tail turned out to do the finding ...
ScienceAlert on MSN
Scientists discover a bizarre new way life can make DNA without DNA
A molecular illustration of the crowded interior and cell envelope of Escherichia coli. (David S. Goodsell, The Scripps ...
Researchers have used AI to uncover the DNA signature of a key genetic “switch” involved in turning genes on. After analyzing ...
In our cells, countless RNA polymerase (RNAP) enzymes zip along our DNA, rotating and twirling in an elaborate molecular ...
Genetic analysis of bison dating back 20,000 years shows how the 19th-century slaughter reshaped the species—and how today's ...
CRISPR/Cas9-induced DNA double-strand breaks (DSBs) are widely used for genome engineering, yet their capacity to provoke sister chromatid exchange (SCE) and associated genome instability remains ...
Every time a cell divides, it must accurately copy its entire genetic instruction manual. Before this process can begin, cells load their DNA-copying motor—a complex of six subunits known as the ...
Distinct properties of glutamate-dopamine, nonglutamate-dopamine, and glutamate-only ventral tegmental area neurons Combined, our analyses designated 126 genes as FIRST genes. As anticipated, FIRST ...
Scientists have found the first direct evidence of the powerful role our genetic makeup plays in influencing our risk of cancer, with inherited genes interacting with acquired genetic mutations to ...
Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment has been the focus of a 30-year research question. New work from the Crick ...
Balancing replication fork progression and origin usage is essential to maintain genome stability, but measuring replication fork progression rates and origin usage throughout the genome has been ...
Applying new analytic methods to nearly 16,000 ancient genomes reveals natural selection has acted on hundreds, not dozens, of genes in West Eurasia over the last 10,000 years. More than half of the ...
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