The San Francisco 49ers and the Jacksonville Jaguars square off in Week 4 of the NFL regular season today. Here's the start time and where to watch.

The NFL has made a major schedule change, flexing the 49ers-Buccaneers into a late slot and pushing down Patriots-Saints.

NFL Week 5 odds, picks, predictions, TV channel, streaming information for Thursday Night Football game between San Francisco ...

San Francisco 49ers QB Brock Purdy woke up Monday with "real soreness" in his injured toe after playing in Sunday's loss to ...

The San Francisco 49ers ran into an old friend on Sunday. Jacksonville Jaguars defensive lineman Arik Armstead had a 'special ...

49ers receiver Ricky Pearsall is now questionable to return with a knee injury. The San Francisco 49ers cannot seem to shake ...

San Francisco 49ers quarterback Brock Purdy is once again dealing with a toe issue after returning to the lineup on Sunday.

The 49ers will re-evaluate Brock Purdy’s sore toe from Sunday’s loss to the Jaguars and with a Thursday game fast approaching ...

The 49ers never did sack Jacksonville quarterback Trevor Lawrence, whose jersey was kept clean while going 21-for-31 for 174 ...

San Francisco 49ers defensive coordinator Robert Saleh and Jacksonville Jaguars head coach Liam Coen had to be separated ...

The NFL season continues with the San Francisco 49ers hosting the Jacksonville Jaguars Sunday. Start time, where to watch, streaming and NFL schedule.

Call it the Mac Jones bowl when the San Francisco 49ers and the Jacksonville Jaguars meet in Week 4. Here's how to watch and more.