“ South Park ” kicked off its 27th season on Wednesday night, and in the debut episode, Trey Parker and Matt Stone literally put Donald Trump in the White House and in bed with the Devil.

Parker was asked for his reaction to the fracas as he sat on the stage at San Diego’s Comic-Con International at the beginning of a Comedy Central animation panel that also included his “South Park” partner Matt Stone, “Beavis and Butt-Head” creator Mike Judge, and actor Andy Samberg, who co-created the animated “Digman!”