GNPC: Mining 40,000 Fluid Samples for Neurodegeneration Markers . Add To My AlzForum; 27 Jun 2025. Assembled by the Global Neurodegeneration Proteomics Consortium, the dataset represents the largest ...

A documentary of country legend Glen Campbell's life and “Goodbye Tour” following his diagnosis of Alzheimer's ...

Missense mutations in LRRK2 were first identified as a cause of Parkinson’s disease (PD) in 2004. Subsequent studies showed that these mutations account for up to 10 percent of familial cases, with ...

Species: Mouse Genes: MAPT Mutations: MAPT P301L Modification: MAPT: Transgenic Disease Relevance: Alzheimer's Disease, Frontotemporal Dementia Strain Name: Thy1-hTau.P301L Genetic Background: FVB/N ...

Overview. Pathogenicity: Alzheimer's Disease : Pathogenic, Cerebral Amyloid Angiopathy, Down's Syndrome ACMG/AMP Pathogenicity Criteria: PS1, PS2, PS3, PS4, PM1 Clinical Phenotype Studied: Alzheimer's ...

Li-Huei Tsai, Massachusetts Institute of Technology, Boston, and colleagues some years ago turned light and sound into a therapy.They called it GENUS, short for gamma entrainment using sensory stimuli ...

Dennis Selkoe Co-Director, Brigham and Women's Hospital's Ann Romney Center for Neurologic Diseases; Posted: 21 Mar 2019 This morning’s news that an interim analysis by Biogen of their Phase 3 ...

David Holtzman Washington University; Posted: 27 Jul 2018 The new data clearly showed that the anti-Aβ antibody BAN2401 was able to significantly remove amyloid from brain, as quantified by ...

It has been clear for a while that anti-amyloid antibodies can sweep plaque from the brain, but until now the question of whether this slows cognitive decline has remained hotly contended. Despite ...

20 Jan 2022. After months of uncertainty, the hammer fell for Biogen: In a draft decision released January 11, the Centers for Medicare and Medicaid Services proposed to cover the anti-amyloid ...

22 Jul 2022. The Alzheimer’s field was rocked this week by allegations against Sylvain Lesné at the University of Minnesota, Minneapolis. Lesné stands accused of manipulating data images in multiple ...

28 Sep 2022. Eisai and Biogen yesterday announced positive topline results from the Phase 3 Clarity trial of their anti-amyloid antibody lecanemab.The drug slowed decline on the primary endpoint, ...