A 41-year-old man was evaluated for swelling in the ankles and syncope. CT of the chest showed bilateral mediastinal and ...

For over 200 years, the New England Journal of Medicine (NEJM) has brought important medical news to the world’s most influential physicians. The global medical community, physicians ...

Tirzepatide is a long-acting agonist of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptors that results in 12 to 21% weight loss in patients with obesity; however ...

1 Section of General Internal Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT 2 Department of Health Policy and Management, Yale School of Public Health ...

The advent of new drugs to treat tuberculosis and enhanced ... the Institute of Tropical Medicine supported site laboratories and performed additional testing. Procedures included smear microscopy ...

The development of simple, reliable ultraviolet and visible spectrophotometers within the last ten years has made available an analytical tool of great versatility and power. The role played by ...

Allogeneic hematopoietic stem-cell transplantation is the only curative treatment for myelofibrosis. Driver mutations are the pathophysiological hallmark of the disease, but the role of mutation ...

Multiple diseases in children have been linked to manufactured synthetic chemicals, which are subject to few legal or policy constraints. A revamping of law and restructuring of the chemical ...

New catheter materials for peripherally inserted central catheters (PICCs) may reduce the risk of device failure due to infectious, thrombotic, and catheter occlusion events. However, data from ...

A quantitative alcohol history should be recorded for all patients, because alcohol use contributes to many physical and mental disorders. A person-centered, nonjudgmental approach should be ...

This Journal feature begins with a case vignette ... inhibitors to reduce the risk of hospitalization for heart failure. New cardiometabolic drugs such as glucagon-like peptide-1 agonists have ...

Panel A summarizes the conventional model of how oncogenic RAS guanosine triphosphatases (i.e., Kirsten rat sarcoma viral oncogene homologue [KRAS], neuroblastoma RAS viral oncogene homologue ...