Brandon Aiyuk hasn't played an NFL game since his serious knee injury in 2024. Here's why he won't be playing at all in 2025.

The Tennessee Titans have a tough road game ahead of them in Week 15 when they face the San Francisco 49ers at Levi's Stadium ...

The Tennessee Titans and the San Francisco 49ers meet Sunday in Week 15 in Santa Clara, California, with kickoff slated for 4 ...

The Tennessee Titans are heading out west to take on Brock Purdy, Christian McCaffrey and the San Francisco 49ers at Levi's ...

Our experts' predictions are in for Tennessee Titans vs. San Francisco 49ers on Sunday. Here's who our experts are picking to ...

Just 24 hours before their Week 15 matchup vs. the Tennessee Titans, the San Francisco 49ers got a concerning update on ...

San Francisco 49ers star running back Christian McCaffrey was added to the team's injury report Saturday due to a back injury ...

The San Francisco 49ers have placed receiver Brandon Aiyuk on the reserve/left squad list, making him ineligible to return ...

On Saturday, the San Francisco 49ers announced the following roster moves ahead of Sunday's game against the Tennessee Titans ...

Riding a three-game winning streak into the Bye Week had to have put the San Francisco 49ers on cloud nine. But what probably ...

The Athletic's Dianna Russini is expecting an answer in the near future as to whether Brandon Aiyuk will play another game ...

The 2025 season has been an up-and-down one for San Francisco 49ers quarterback Brock Purdy. After leading his team to a game ...