Researchers from Queen Mary University of London's School of Biological and Behavioral Sciences, using the simple fission yeast as a model, have shown that the new TOR inhibitor rapalink-1 prolongs ...

Study in fission yeast revealed a key role for a set of enzymes called agmatinases, which break down the metabolite agmatine into polyamines.

Rapamycin, competing with other rapalogs, activates TRPM8 via directly binding to a novel binding site, which results in providing new insights into the mechanisms of TRPM8 activation.

Researchers identify LRP8 as the essential receptor for tick-borne encephalitis virus in brain cells, offering new targets for antiviral therapy.

Hugo W. Moser Research Institute, Michael V. Johnston Center for Developmental Neuroscience, Kennedy Krieger Institute, Baltimore, United States Department of Neurology, Johns Hopkins School of ...

Explore what FDA approval of elamipretide means for ultra-rare disease drug development and the outlook for future biotech innovators.