Serine serves as a metabolic nexus in tumors, coordinating one-carbon metabolism, nucleotide synthesis, and redox regulation.

The amount of any given protein in a cell has to be controlled to keep its levels within a range required for healthy functions. This is especially important for proteins that are known to group ...

For years, the pancreas has been being taught in biology class as an easy system: insulin lowers blood sugar, and glucagon ...

The intestinal epithelium plays a crucial role in maintaining gut health and homeostasis. It serves as a barrier that protects the body from pathogens and regulates nutrient absorption. Recent ...

Before a chain of amino acids can become an active and useful protein, it must be processed and folded into the appropriate ...

Cells are crowded with proteins and nucleic acids. A new study measures subcellular densities across organisms to uncover how ...

The unfolded protein response (UPR) is a protective pathway that helps cells manage stress during protein production. Cancer ...

In the march of metastasis, a molecular trail of crumbs guides some cancer cells from the primary tumor to establish new ...

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with a five-year survival rate below 10%.

A research team led by Prof. Wang Yi and Wei Haiming from the University of Science and Technology of China (USTC), in ...

The intestinal epithelium forms a dynamic barrier that not only mediates nutrient absorption but also provides a critical line of defence against microbial pathogens. Its homeostasis is maintained ...