The amount of any given protein in a cell has to be controlled to keep its levels within a range required for healthy functions. This is especially important for proteins that are known to group ...

For years, the pancreas has been being taught in biology class as an easy system: insulin lowers blood sugar, and glucagon ...

Before a chain of amino acids can become an active and useful protein, it must be processed and folded into the appropriate ...

The intestinal epithelium forms a dynamic barrier that not only mediates nutrient absorption but also provides a critical line of defence against microbial pathogens. Its homeostasis is maintained ...

Cells are crowded with proteins and nucleic acids. A new study measures subcellular densities across organisms to uncover how ...

The unfolded protein response (UPR) is a protective pathway that helps cells manage stress during protein production. Cancer ...

Purdue University scientists are deciphering an intricate cellular signaling system critical to immune response to better understand how it could be used to address multiple diseases, including cancer ...

A research team led by Prof. Wang Yi and Wei Haiming from the University of Science and Technology of China (USTC), in ...

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with a five-year survival rate below 10%.

An engineered viral protein enhanced the anticancer function of T cells in mice, suggesting a new strategy to improve immunotherapy. Courtney and his team sought to exploit this property of TIP to ...