Investigators studied apixaban pharmacokinetics, pharmacodynamics, and hemorrhage risk by kidney function. Kidney function is a major predictor of hemorrhage among patients with atrial fibrillation ...

A recent study published in JAMA has found that certain blood pressure medications may raise the risk of serious bleeding in ...

Purpose The pharmacology, pharmacokinetics, efficacy, and safety of apixaban are reviewed. Summary Apixaban is an oral, direct, selective factor Xa inhibitor with a rapid onset of action. It has a ...

Apixaban is currently indicated in Europe for the prevention of VTE in patients who have undergone total knee replacement or total hip replacement. Apixaban is also being investigated in Phase III ...

People with type 2 diabetes who used semaglutide (Ozempic) versus other drugs had a lower risk of Alzheimer's disease and ...

Apixaban is 25% hepatically metabolized and a substrate for P-gp. 2 The enzyme mainly responsible for this metabolism is CYP3A4 with CYP1A2, 2C8, 2C9, 2C19, and 2J2 playing minor roles. 2 Apixaban ...

Extended anticoagulation using reduced-dose apixaban was found to be noninferior to using full-dose apixaban in preventing recurrent venous thromboembolism (VTE) in patients who had active cancer ...

Eliquis (apixaban) is an anticoagulant used to lower the chance of stroke in people with atrial fibrillation (AFib), a common type of irregular heartbeat (arrhythmia). Most Medicare prescription ...