Panelists discuss that, based on EMERALD trial data, elacestrant provides consistent clinical benefit in metastatic breast cancer regardless of ESR1 mutation allele frequency, supporting the use of ...

We propose the Probabilistic YIN (PYIN) algorithm, a modification of the well-known YIN algorithm for fundamental frequency (F0) estimation. Conventional YIN is a simple yet effective method for frame ...

Israel launches strikes on missile facilities in central Iran: air force Incyte (Nasdaq:INCY) today announced the first clinical data from two studies evaluating the safety, tolerability and efficacy ...

We collected data from 100 individuals at four time points, obtaining both allele frequencies from Pool-seq and genotypes from individual sequencing (Fig. 1 A and C). This time series genomic data ...

Type 1 diabetes mellitus (T1DM) is defined as an autoimmune disorder and has enormous complexity and heterogeneity. Although its precise pathogenic mechanisms are obscure, this disease is widely ...

The effect of allele frequency is clearly seen in the population means. If, for instance, the objective is to develop earlier flowering lines, the best strategy is to perform at least one, preferably ...

Using the Low Frequency Array (LOFAR), European astronomers have investigated a galaxy cluster designated CIZA J2242.8+5301, dubbed the Sausage cluster. The observations conducted at very low ...