In prokaryotes, the DNA (chromosome) is in contact with the cellular cytoplasm and is not in a housed membrane-bound nucleus. In eukaryotes, however, the DNA takes the form of compact chromosomes ...

Most prokaryotes have a circular genome that is simply copied and then put into a daughter cell, while the replication of chromosomes, and the careful segregation of the new copies into two new cells ...

Eukaryotic cells must tightly fold their DNA so that it fits within the cellular nucleus. Supercoiled DNA is tightly packed inside the chromosomes.

For all species, the process of DNA replication requires the use of multiple different DNA polymerase enzymes.

Unlike eukaryotes, which utilize the GTPase tubulin to segregate DNA, the most common plasmid-encoded NTPases contain Walker-box and actin-like folds. Recently, a plasmid stability cassette on ...

Eukaryotic cytosine methylation represses transcription but also occurs in the bodies of active genes, and the extent of methylation biology conservation is unclear. We quantified DNA methylation in ...