The EMBO Journal11d
The dynamics of loss of heterozygosity events in genomes
This month's cover highlights the article A novel bacterial effector protein mediates ER-LD membrane contacts to regulate ...
The EMBO Journal8d
Macrophage-induced enteric neurodegeneration leads to motility impairment during gut inflammation
This study investigates the impact of myenteric neuron-macrophage interactions on postoperative trauma and subsequent ...
The EMBO Journal4d
Oncolytic viruses expressing MATEs facilitate target-independent T-cell activation in tumors
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Oncolytic adenoviruses were designed to reach ...
The EMBO Journal8d
RHEB neddylation by the UBE2F-SAG axis enhances mTORC1 activity and aggravates liver tumorigenesis
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Small GTPase RHEB is a well-known mTORC1 ...
The EMBO Journal12d
Cohesin positions the epigenetic reader Phf2 within the genome
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Genomic DNA is assembled into chromatin by ...
The EMBO Journal7d
Partitioning of fatty acids between membrane and storage lipids controls ER membrane expansion
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Biogenesis of membrane-bound organelles ...
The EMBO Journal12d
A therapeutic regimen using neoantigen-specific TCR-T cells for HLA-A*2402-positive solid tumors
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The adoptive transfer of TCR-T cells specific ...
The EMBO Journal12d
MCTS2 and distinct eIF2D roles in uORF-dependent translation regulation revealed by in vitro re-initiation assays
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. This study explores the mechanisms of ribosome ...
The EMBO Journal8d
PlexinD1 is a driver and a therapeutic target in advanced prostate cancer
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Aggressive prostate cancer (PCa) variants ...
The EMBO Journal5d
Oncolytic viruses expressing MATEs facilitate target-independent T-cell activation in tumors
This month's cover highlights the article JAK-STAT1 as therapeutic target for EGFR deficiency-associated inflammation and scarring alopecia by Karoline Strobl, Maria Sibilia, Thomas Bauer and ...
The EMBO Journal5d
Acidic pH can attenuate immune killing through inactivation of perforin
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Cytotoxic lymphocytes are crucial to our ...