Federal agencies across government can resume laying off their employees en masse after the Supreme Court reversed a court order that barred those reductions, with several agencies likely to move swiftly to start cutting staff.

The U.S. Supreme Court on Tuesday cleared the way for Donald Trump's administration to pursue mass government job cuts and the sweeping downsizing of numerous agencies, a decision that could lead to tens of thousands of layoffs while dramatically reshaping the federal bureaucracy.

Tens of thousands of federal workers have been fired, have left their jobs via deferred resignation programs, or have been placed on leave.