Biologists are closing in on a puzzle that seems to turn classic evolutionary logic inside out, yet may be so common that it deserves to be called a new rule of life. Instead of always purging harmful ...

New work by Columbia researchers has turned a textbook principle of genetics on its head and revealed why some people who carry disease-causing genes experience no symptoms. Every biology student ...

When a wound does not heal properly, it leaves a scar. Similarly, mutations—which are permanent changes to genetic code—are often the result of damaged DNA that has not been properly repaired.

Newswise — A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, ...

After an allogeneic stem cell transplant, a recipient’s body faces a daunting task: rebuilding the person’s blood-forming and immune systems from the ground up from a relatively small number of “seed” ...

A new study shows that newly acquired cell mutations interact with inherited mutations—those passed down by your parents—in important ways that influence your lifetime cancer risk. As we age, our ...

Researchers at the University of Oslo and Oslo University Hospital have developed a promising new immunotherapy targeting the CTNNB1 gene mutation associated with various aggressive cancers like lung ...

Researchers have shown that RNA droplets trap their own DNA templates, and that even low rates of mutation produce stable ...

New study demonstrates how high-affinity B cells 'bank' their best traits instead of rolling the dice and risking deleterious mutations, with implications for better vaccine design. A vaccine's ...