In medicinal chemistry, the binding affinity of a small-molecule scaffold (possibly discovered through a fragment-based approach) for a therapeutic target is optimized from millimolar to nanomolar ...

The life of the clutch, being an integral component of the transmission, directly impacts the gearbox's stability. A finite element model and a thermodynamic numerical method of a multi-disc clutch ...

Cylinder deactivation is a proven solution to improve vehicle fuel economy. This proposal presents Dynamic Cylinder Deactivation (DCD) solution to the conventional automotive engines. DCD is an engine ...