A prominent protein on most human cells may be key to unlocking the code that makes humans susceptible to pathogenic bacteria and viruses, including human immunodeficiency virus (HIV), according to a ...
AI-designed T-cell receptors improved cancer-cell killing in the lab and tumor control in mice, pointing toward more ...
A mouse study found that removing ANKRD11 enhanced CD8+ T-cell activity against chronic hepatitis B virus infection and ...
T cell receptor-engineered T cells can recognize peptide fragments of intracellular proteins, offering a route to treating hepatocellular carcinoma that is not restricted to proteins exposed on the ...
Researchers used a CRISPR screen to identify a key molecular pathway that drives exhaustion in cancer-fighting immune cells, ...
Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system. St. Jude Children's Research Hospital scientists recently ...
A research team from the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health have discovered how the ...
Chimeric antigen receptor T cell (CAR-T) therapies have revolutionized treatment for various blood cancers. When traditional treatments fail, CAR-T therapies provide a second highly effective option.
Researchers at the UCLA Health Jonsson Comprehensive Cancer Center used a CRISPR screen to identify a key molecular pathway that drives exhaustion in cancer-fighting immune cells, limiting their ...
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