A challenge in the computational design of enzymes is that multiple properties, including substrate binding, transition state stabilization and product release, must be simultaneously optimized, and ...

A team of researchers led by the National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN) and Osaka University established a new method to measure glomerular filtration rate (GFR), ...

E. coli cells have now been engineered into producing large quantities of serine, which is used in detergents, tube feeding formula, and as building blocks for many important chemicals. Using the ...

Of the 37 million patients in the U.S. with Type 2 diabetes, about half of them suffer from peripheral neuropathy, according to National Institutes of Health estimates. The condition causes numbness, ...

In 2001, researchers noticed that serine—unlike other amino acids—formed a charged, eight-membered cluster during electrospray ionization mass spectrometry (Anal. Chem. 2001 DOI: 10.1021/ac010284l).

Studies in mice by a Salk Institute research team have shown how altered amino acid metabolism can represent a contributing factor to diabetes-associated peripheral neuropathy. Their experiments found ...

D-serine as an adjunctive treatment did not outperform placebo overall in patients with major depressive disorder (MDD), a new trial showed. However, depressive symptoms and anhedonia were ...

A dietary supplement believed to protect against Alzheimer's disease might instead be potentially harmful to the brain, a new study warns. L-serine is an amino acid that serves many different roles in ...

A team of researchers has established a new method to measure glomerular filtration rate (GFR), a primary kidney function, by calculating the clearance of D-serine. A team of researchers led by the ...

A team of researchers led by the National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN) and Osaka University established a new method to measure glomerular filtration rate (GFR), ...