Synthetic biochemistry seeks to engineer complex metabolic pathways for chemical conversions outside the constraints of the cell. Establishment of effective and flexible cell-free systems requires the ...

St. Jude Children's Research Hospital scientists have determined how a protein's disordered region serves as a molecular rheostat to help regulate cell survival. The survival drama is played out ...

Researchers have found a switch that regulates the activity of HNF1A, a gene that causes diabetes. The study highlights potential new vulnerabilities in the disease and could lead to the development ...

Rheostats are simple and ubiquitous circuit elements, usually comprising a potentiometer connected as an adjustable two terminal resistor. The availability of manual pots with resistances spanning ...

Rheostat Therapeutics, a young biotech firm focused on treatments for neurodegeneration, cognition, and rare diseases, secured $23 million in its first formal round of funding. Rheostat is developing ...