Researchers mapped myelin-making cells in mice, showing some brain regions recover better after myelin damage.

Researchers say study identifies location of oligodendrocytes in the brain, and integrates information about gene expression and the structural features of neurons.

The central nervous system (CNS) critically depends on the integrity of oligodendrocytes, specialised glial cells responsible for the formation and maintenance of myelin sheaths. Myelin not only ...

To rapidly transmit electrical signals in the brain, the long nerve fibers are insulated by specialized cells called oligodendrocytes. These cells also respond to the electrical signals of active ...

Johns Hopkins scientists say they have used 3D imaging, special microscopes and artificial intelligence (AI) programs to construct new maps of mouse brains showing a precise location of more than 10 ...

Oligodendrocytes are an important source of amyloid beta (Aβ) and play a key role in promoting neuronal dysfunction in Alzheimer's disease (AD), according to a study published July 23, 2024 in the ...

Myelin sheaths are critical for efficient signal transmission along axons. Their inactivation could explain some of the neuropathological deficits associated with schizophrenia. In the April 10 ...

Researchers from Institute of Genetics and Developmental Biology of Chinese Academy of Sciences generated mice with conditional knockout (cKO) of Mea6 in oligodendrocytes. Using different models of ...

The APOE4 variant causes cholesterol buildup in the cells that make protective fatty sheaths for neurons, possibly helping explain its role in neurodegeneration. Using transcriptomic profiling, the ...