Arizona’s 24-23 win on Oct. 6 of last season, a game in which the 49ers led 23-10, helped chart the path to a 6-11 season.

The 49ers (3-0) won their home opener 16-15 on Eddy Pineiro’s walk-off field goal against the Arizona Cardinals.

The Niners are without their starting quarterback, Brock Purdy, and have Mac Jones at the helm. He struggled with turning the ...

The San Francisco 49ers haven’t had the luxury to not win ugly in their uphill battle through just three weeks of the NFL season.

The San Francisco 49ers will take on the Atlanta Falcons on Sunday at Levi's Stadium. Here's who is set to practice on ...

The 49ers were dealt a blow in their quest to trade for Trey Hendrickson from the Bengals in the wake of Nick Bosa's ...

With injuries to key stars, San Francisco is still finding ways to dominate opposing offenses thanks its defensive ...

The Arizona Cardinals will face the San Francisco 49ers in Week 3 of the NFL season on Sunday at Levi's Stadium.

Brock Purdy has been out of action for the San Francisco 49ers with a turf toe injury, but the quarterback will eventually ...