The MAP kinase and PI3 kinase signaling pathways are among the best understood signal transduction pathways. The MAP kinase pathway is a major mitogenic signaling pathway activated by receptor protein ...

Mitogen-Activated Protein Kinase (MAPK) pathways are crucial signaling routes that mediate multiple cellular processes, ...

Heritable biochemical idiosyncrasies are thought to help explain the variable outcome when individuals in the outbred human population are exposed to pathogens. However, even in relatively tractable ...

Mitogen-Activated Protein Kinase (MAPK) signalling cascades are fundamental to the regulation of numerous cellular processes, including stress response, inflammation, cell cycle control and apoptosis.

Researchers from Medical University Vienna presented data from a study that aimed to identify possible synergism between the novel son of sevenless (SOS) inhibitor BAY-293 and B-Raf or/and MEK1/2 ...

NOTE. P < .00357 represents statistical significance after the Bonferroni correction. Abbreviations: MAPK, mitogen-activated protein kinase; NA, unable to be calculated; NR, not reached; OS, overall ...

Sulforaphane is an antioxidant and a potent stimulator of natural detoxifying enzyme and associated with lowered risk of cancer that is associated with the consumption of cruciferous vegetables. The ...

Scientists from the University of Colorado, Boulder (CU Boulder), have published new research in Science Advances that shows that endogenous retroviruses (ERVs)—“junk DNA”—in the genome can play a ...

Actionable Tumor Alterations and Treatment Protocol Enrollment of Pediatric and Young Adult Patients With Refractory Cancers in the National Cancer Institute–Children's Oncology Group Pediatric MATCH ...

A Nigerian researcher, Muinat Zubair, has developed a method for predicting protein structure and protein-protein interactions using a combination of experimental and computational approaches.Zubair ...

In a recent study under review at the journal Molecular Medicine and currently available on the Research Square* preprint server, researchers in China investigate the role of phosphatidylinositol 3 ...