Researchers at the University of São Paulo (USP) in Brazil have succeeded in showing, in an animal model, that the process of insulin resistance in the brain affects both Alzheimer's disease and ...

Overview of peripheral and central insulin actions (black arrows). The vast majority of insulin hormones are synthesized by the pancreas. Insulin crosses the blood‒brain barrier (BBB) to act within ...

When lipid biologist Usha Acharya at the National Cancer Institute (NCI) tinkered with lipid breakdown pathways in Drosophila melanogaster, she observed something intriguing. Blocking a biochemical ...

A clinical trial from Wake Forest University School of Medicine shows that two widely available medications, the diabetes drug empagliflozin (Jardiance) and intranasal insulin, safely improve brain ...

Developing resistance to insulin is a key step on the road to diabetes, making insulin resistance a target for treating metabolic dysfunction. Insulin orchestrates blood glucose levels by signaling ...

Three years ago, the inceptor protein was discovered and its role as an inhibitor of the insulin signaling pathway was described. Inceptor and the insulin receptor are located on the surface of beta ...

Craig Beall currently receives funding from Diabetes UK, Breakthrough T1D, Steve Morgan Foundation Type 1 Diabetes Grand Challenge, Medical Research Council, NC3Rs, Society for Endocrinology and ...

Over the 40-minute period after intranasal insulin administration, elevated standard uptake values were observed in 11 regions. HealthDay News — Intranasal administration of [68 Ga]Ga-NOTA-insulin is ...