Scientists from Oxford's Radcliffe Department of Medicine have achieved the most detailed view yet of how DNA folds and ...

Scientists are hopeful it will improve understanding of how genes work, what goes wrong in disease, and how to fix it.

Anne van Schoonhoven is in the Departments of Pulmonary Medicine and of Cell Biology, Erasmus University Medical Center, Rotterdam 3015 GD, the Netherlands. Ralph Stadhouders is in the Departments of ...

The laws of inheritance are quite unknown,” Charles Darwin acknowledged in 1859. The discovery of DNA’s shape altered how we ...

Nucleome is backed by a world-class syndicate of investors: M Ventures, the venture capital arm of Merck KGaA; Johnson and Johnson Innovation - JJDC, Inc. ("JJDC"); Pfizer Ventures; British Business ...

DNA is the genetic material used by every living organism. But, in a few edge cases, the four bases of DNA—adenine, thymidine, cytosine, and guanine—undergo chemical modifications. And in viruses, ...

CRISPR-Cas9 has been editing the human genome for the past decade. Although the types of edits have varied, an unsolved challenge has been the integration of large pieces of DNA without ...

Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and replace them with new ones, in a safer and more efficient way. Using this system ...