By Pooja Toshniwal Paharia Preclinical studies increasingly place circular RNAs at the intersection of thermogenic programming and organelle stress control, raising the possibility that these stable ...

Propagation of expression noise from mRNA to protein level is influenced by variation in availability of ribosomal machinery.

GAO Caixia's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences (CAS) has developed a new method of downregulating gene translation to a predictable and ...

DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning ...

siMecA-AGO2 complex inhibits the translation of the mecA gene which encodes the penicillin-binding protein 2a (PBP2a), a protein at the heart of the drug-resistance phenotype in MRSA. By reducing ...

RNA therapeutics target translation rather than DNA, aiming to correct shared protein production errors. By enabling cells to read through premature stop codons, engineered tRNAs could restore ...

RNA modification is a key regulator of neuroblastoma oncogenesis and differentiation. NSUN6, a 5-methylcytosine-specific messenger ...

MicroRNAs—snippets of nucleic acids a couple dozen base pairs in length—are so small that they went unnoticed for decades despite wielding enormous influence in our cells. It’s now known that they ...

Targeting ACVRL1, dubbed an 'overlooked' gene by researchers, could potentially lead to new treatments for IPF, a study suggests.

A protein’s life is anything but simple. Discover how transcription, translation, folding, modification, and degradation work together to preserve proteome integrity.