A number of membrane proteins that are present on the cell membrane control external and internal material transportation, cell protection and signal transmission. The diversity of functions of ...

G protein-coupled receptors (GPCRs) represent the largest family of cell surface receptors, orchestrating a vast array of physiological responses by transducing extracellular signals into ...

During lactation, the mammary gland undergoes significant structural and functional changes to produce milk, which is ...

Researchers used AlphaFold3, the latest AI-based protein modeling system, to predict the structures of all 25 known human ...

Researchers at University of California San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse ...

We are working on medicines* to fulfill unmet needs. We believe that small-molecule therapies targeting G-protein-coupled receptors (GPCRs) have the potential to transform the lives of patients with ...

In the search for answers about Alzheimer’s disease, researchers are taking a close look at the immune system of the brain. A ...

If future studies confirm the rescued receptors work normally, the study offers a new roadmap for rare disease drug development.

Researchers in Germany have uncovered a hidden receptor, GPR133, that plays a vital role in bone strength. By activating it ...

AbbVie is paying $255 million cash to acquire British biotech DJS Antibodies and its platform for targeting transmembrane proteins. DJS is focused on difficult-to-drug disease-causing proteins, such ...