Cell behaviour is regulated by myriad external stimuli that act through specialized receptor proteins at the cell surface. G-protein-coupled receptors (GPCRs) are the largest family of receptors and ...

Structural biology techniques helped researchers target the nuclear receptor-binding SET domain family for the first time; its malfunction is associated with several types of cancer. A team of ...

Even as the COVID-19 pandemic continues to smolder and flare up in various parts of the world, researchers are still trying to make sense of the virus, its routes of spread, its target tissues, and ...

HTRF uses two fluorophores, a donor and an acceptor, to label proteins or other targeted biomolecules. When these ...

Researchers from the National Institute for Physiological Sciences/the Exploratory Research Center on Life and Living Systems (ExCELLS)/the Graduate University for Advanced Studies (SOKENDAI) in Japan ...

Illinois professor Uwe Rudolph, left, and research scientist Maltesh Kambali led an international group of researchers who found a key role for an enzyme regulating glycine in the brain while ...

Research published today (Jan. 22) in the journal Brain reveals a new approach to Alzheimer’s disease (AD) that may eventually make it possible to reverse memory loss, a hallmark of the disease in its ...

Researchers at the University of Michigan (U-M) Rogel Cancer Center say they have developed the first drug-like compounds to inhibit a key family of enzymes whose malfunction is associated with ...

Chronic pain is one of the most common and expensive health problems in the nation, affecting an estimated one in five U.S. adults and costing around $600 billion each year in medical expenses, lost ...