The dentate gyrus (DG) is a region of the mammalian brain known to support the encoding of new memories. This brain region is part of the hippocampal formation, a set of brain regions involved in ...

The dentate gyrus is one of only two areas in the brain where new neurons are formed continuously in adults through a process called neurogenesis. When a new granule cell neuron is formed in the ...

It appears that new cells compete to ‘win’ synapse connections away from old cells, which promotes network plasticity. Linda Overstreet-Wadiche, Ph.D. One goal in neurobiology is to understand how the ...

Left: In the dentate gyrus of the hippocampus of 4-5 month-old Rp58 heterozygous-KO mice, DNA damage accumulates in the mossy cells (yellow-green) (ssDNA; red), and the surrounding microglia (blue) ...

Age-related memory decline may be reversed with high doses of naturally occurring cocoa flavanols, US researchers have discovered in findings that establish the dentate gyrus as central to cognitive ...

Researchers have found the first evidence that selective activation of the dentate gyrus, a portion of the hippocampus, can reduce anxiety without affecting learning. The findings suggest that ...

In the process of solving a decades-long mystery about a particular protein, scientists have identified a specific location in the brain where schizophrenia may originate. The news: Despite the ...

Researchers present data and a simple statistical network model that describe an unanticipated property of newly formed, immature neurons in the dentate gyrus. The model resolves a seeming paradox in ...