Skeletal stem cells (SSCs) are essential for bone development, homeostasis, and repair. Recent studies have identified distinct SSC populations in long bones, craniofacial bones, and spine. Techniques ...

Growth plates are areas of cartilage found at the ends of long bones. They play a role in the bone growth of children and teens. An injury to a growth plate can affect the development of a bone. While ...

Endochondral bone development is the principal mechanism by which the vertebrate skeleton forms, involving the replacement of a transient cartilage template with mineralised bone. Mesenchymal cells ...

In vertebrates, the skeleton of different regions of the body arises from different precursor cells. Researchers have now discovered that these skeletal cells do not just differ in their developmental ...