An international research team led by Osaka University has identified a new mechanism crucial for the initiation of autophagy, a self-degradation process cells use to eliminate unneeded or damaged ...

Upon autophagy induction, ZDHHC13 is recruited to autophagosome formation sites together with ATG9A. ULK1 is palmitoylated at Cys 927 and Cys 1003 residues by ZDHHC13, and the ULK1 complex are ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...

Autophagy, which literally means "self-eating," is a cellular cleaning-out process that maintains our bodies in good order, but excessive autophagy can be too much of a good thing. Now Weizmann ...

Autophagy, the cell’s essential 'housekeeping' process, involves degrading and recycling damaged organelles, proteins, and other components to prevent clutter. This vital mechanism, found in all life ...

A review led by Academician Yulong Yin from the Institute of Subtropical Agriculture of the Chinese Academy of Sciences has shed new light on the intricate interplay between exosomes and autophagy—two ...

A study from Chiba University shows that a certain diet can impair memory by disrupting autophagy, a cellular recycling process crucial for neuronal health. Using fruit flies, researchers found ...