New in vitro research shows that free fatty acid–induced steatosis activates a TNF-α/TNFR1–Caspase−8/Caspase−2 apoptotic ...

An international research team has discovered a previously unknown mechanism that plays a key role in the signaling pathways ...

An international research team has discovered that the protein HERC4 is a key component in the signalling pathways involved in programmed cell death, which is responsible for triggering inflammatory ...

A new study shows that a necroptotic-to-apoptotic cell death axis in intestinal epithelial cells, driven by TNF and interferon gamma, appears in early inflammatory bowel disease lesions and can ...

Apoptosis, or programmed cell death, is a tightly regulated biological process necessary for normal tissue maintenance and development. However, aberrations in apoptotic signaling networks are ...