Philosophical Transactions: Biological Sciences, Vol. 369, No. 1633, Synaptic plasticity in health and disease (5 January 2014), pp. 1-7 (7 pages) The prevailing view at present is that postsynaptic ...
For all glutamate-gated channels, agonist-binding in the cleft formed by two dynamic lobes, D1 and D2, of ligand-binding domains (LBDs) is the event that energizes resting receptors to either open or ...
NMDA receptor (NMDAR) activation controls long-term potentiation (LTP) as well as long-term depression (LTD) of synaptic transmission, cellular models of learning and memory. A long-standing view ...
Drugs that act on NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, are key for treating neuropsychiatric disorders. These drugs were ...
The difference between mental health and mental illness can turn on changes in brain cells and their connections that are almost incomprehensibly tiny, at least in physical terms. This irony is ...
It remains difficult to distinguish anti-NMDA receptor encephalitis from a primary psychiatric disorder, but recent studies have identified clinical features and proposed screening criteria that could ...
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