Alpha-1 adrenergic receptors (α1-ARs) are a subset of G protein-coupled receptors that play a pivotal role in cardiovascular homeostasis. While traditionally recognised for their involvement in ...

The following studies were undertaken to develop a cultured uterine myocyte model which would allow further clarification of the adrenergic signal transduction mechanisms utilized by these myocytes.

Shock is the term used to describe the physiologic state when there is tissue hypoperfusion throughout multiple organs. [1] Decreased tissue perfusion leads to decreased tissue oxygen delivery. Early ...

None of the current superresolution microscopy techniques can reliably image the changes in endogenous protein nanoclustering dynamics associated with specific conformations in live cells.

Medically reviewed by Violetta Shamilova, PharmD Key Takeaways Poor sleep can not only make you feel lousy, but it can also lead to chronic conditions. Implementing healthy habits and relaxation ...

Noradrenaline is a neuromodulator secreted in the brain depending on behavioral context and physiological states of animal, influencing a wide range of physiological functions by modulating brain ...

Individuals with some forms of heart failure are treated with drugs that are known as beta-blockers because they target proteins known as beta-adrenergic receptors (beta-ARs). Now, a potential ...

Why do patients who receive antipsychotic medications to manage schizophrenia and bipolar disorder quickly gain weight and develop prediabetes and hyperinsulemia? The question remained a mystery for ...

Surgeons can now avoid intraoperative floppy iris syndrome during cataract surgery by stopping tamsulosin prior to surgery or going for alternative strategy. Cataract surgeons were much relieved when ...