Although all anti-O2-antigen antibodies enabled activation of the complement system, anti-capsule antibodies were less effective in their stimulation and ability to to form hexameric IgG clusters.

In this article, ACROBiosystems discusses how the complement cascade and it's various components could potentially be leveraged for therapeutic potential in COVID-19, cancer and general inflammation.

Continued activation of complement system damages tissue and blood cells The researchers followed 113 COVID-19 patients for up to one year after their acute SARS-CoV-2 infection and compared them ...

We are studying the role of the complement system in kidneys and brains during health and disease. Traditionally, major complement proteins were shown to be generated by the liver and are functional ...

However, dysregulated activation of the complement system can also have serious detrimental effects, leading to severe inflammation, such as the “cytokine storms” seen in severe COVID-19.

But the markers that were unique to the long covid groups pointed to abnormal activation of the complement system. What is the complement system? Good question.

“Nipocalimab appears to have an effect on lowering but not completely suppressing complement activation, and may thus potentially reduce NMJ damage, while still allowing the complement pathway ...

Continued activation of complement system damages tissue and blood cells The researchers followed 113 COVID-19 patients for up to one year after their acute SARS-CoV-2 infection and compared them ...